2clt

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spinqualitylabelsall models PDB ID 2clt Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image
2clt, resolution 2.67Å ()
Ligands:	,
Activity:	Interstitial collagenase, with EC number 3.4.24.7
Related:	1ayk, 1cge, 1cgf, 1cgl, 1hfc, 1su3, 2ayk, 2tcl, 3ayk, 4ayk, 966c
Structural annotation: Resources: CATH : 2Clta02, 2Clta01, 2Cltb01, 2Cltb02 InterPro : Ipr002477, Ipr001818, Ipr006026, Ipr000585, Ipr006025 Pfam : PF00045, PF00413 UniProt : P03956
Functional annotation: Cellular component: proteinaceous extracellular matrix extracellular space Biological process: metabolic process collagen catabolic process proteolysis Molecular function: zinc ion binding hydrolase activity peptidase activity metal ion binding catalytic activity calcium ion binding collagenase activity metallopeptidase activity interstitial collagenase activity metalloendopeptidase activity
Evolutionary conservation: Toggle Conservation Colors: Rows = identical sequences: Further Information: Caveats, Explanation, Complete Results at ConSurfDB
Resources:	FirstGlance, OCA, RCSB, PDBsum
Coordinates:	save as pdb, mmCIF, xml

Contents 1 CRYSTAL STRUCTURE OF THE ACTIVE FORM (FULL-LENGTH) OF HUMAN FIBROBLAST COLLAGENASE. 2 About this Structure 3 See Also 4 Reference

CRYSTAL STRUCTURE OF THE ACTIVE FORM (FULL-LENGTH) OF HUMAN FIBROBLAST COLLAGENASE.

Template:ABSTRACT PUBMED 16890240

About this Structure

2clt is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

• Matrix metalloproteinase
• Matrix metalloproteinases

Reference

• Iyer S, Visse R, Nagase H, Acharya KR. Crystal structure of an active form of human MMP-1. J Mol Biol. 2006 Sep 8;362(1):78-88. Epub 2006 Aug 4. PMID:16890240 doi:10.1016/j.jmb.2006.06.079