MDM4

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Template:STRUCTURE 3jzo

MDM4 is a 490 amino acid protein containing a RING finger domain and a nuclear localization signal. MDM4 interacts with protein MDM2. Both of these proteins show structure similarity and contain a p53-binding domain in their N terminal.

Contents




3D Structures of MDM4

2cr8 – hMDM4 ZF-RNBP domain – NMR
3dab – hMDM4 + p53 transactivation domain
3fdo, 3jzo, 3jzp, 3jzq, 3jzr, 3jzs – hMDM4 p53-binding domain + peptide
3lbj - hMDM4 p53-binding domain + inhibitor
3dac – hMDM4 (mutant) + p53 transactivation domain
2vyr – hMDM4 N terminal + antibody
3fe7, 3fea, 3eqy - hMDM4 N terminal (mutant) + peptide
2vje, 2vjf – hMDM2 residues 383-446 + hMDM4 residues 428-490

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Joel L. Sussman, Alexander Berchansky

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