1bqr
From Proteopedia
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REDUCED PSEUDOAZURIN
Overview
The crystal structures of oxidized and reduced pseudoazurins from a, denitrifying bacterium, Achromobacter cycloclastes IAM1013, have been, determined at 1.35- and 1.6-A resolutions, respectively. The copper site, in the oxidized state exhibits a distorted tetrahedral structure like, those of other pseudoazurins. However, not only a small change of the, copper geometry, but concerted peptide bond flips are identified. The, imidazole ring of remote His6 has a hydrogen bonding distance of 2.73 A, between N-delta1(His6) and O-gamma1(Thr36) in the oxidized protein. When, the protein is reduced at pH 6.0, the imidazole ring rotates by 30.3, degrees and moves 1.00 A away from the position of the oxidized state. A, new hydrogen bond between N-epsilon2(His6) and O-epsilon1(Glu4) is formed, with a ... [(full description)]
About this Structure
1BQR is a [Single protein] structure of sequence from [Achromobacter cycloclastes] with CU as [ligand]. Structure known Active Site: COP. Full crystallographic information is available from [OCA].
Reference
Crystal structure determinations of oxidized and reduced pseudoazurins from Achromobacter cycloclastes. Concerted movement of copper site in redox forms with the rearrangement of hydrogen bond at a remote histidine., Inoue T, Nishio N, Suzuki S, Kataoka K, Kohzuma T, Kai Y, J Biol Chem. 1999 Jun 18;274(25):17845-52. PMID:10364229
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