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3uxm

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Image:3uxm.png

Template:STRUCTURE 3uxm

Structure Guided Development of Novel Thymidine Mimetics targeting Pseudomonas aeruginosa Thymidylate Kinase: from Hit to Lead Generation

About this Structure

3uxm is a 4 chain structure with sequence from Pseudomonas aeruginosa pao1. Full crystallographic information is available from OCA.

Reference

  • Choi JY, Plummer MS, Starr J, Desbonnet CR, Soutter H, Chang J, Miller JR, Dillman K, Miller AA, Roush WR. Structure Guided Development of Novel Thymidine Mimetics Targeting Pseudomonas aeruginosa Thymidylate Kinase: From Hit to Lead Generation. J Med Chem. 2012 Jan 26;55(2):852-70. Epub 2012 Jan 13. PMID:22243413 doi:10.1021/jm201349f

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