Semaphorin

From Proteopedia

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Template:STRUCTURE 3nvn
 

Semaphorin (SEMA) are membrane proteins which act as axonal growth guidance molecules. SEMA act as short-range inhibitory signal. There are 8 classes of SEMA numbered 1 to 7 and V (viral). Each class has several subgroups which share similar characteristics.

3D structures of semaphorin

SEMA 3

1q47 – mSEMA 3A – mouse

SEMA 4

1olz – hSEMA 4D extracellular domain – human

3ol2 - hSEMA 4D extracellular domain + plexin-B1

SEMA 6

3afc, 3okw - mSEMA 6A extracellular domain

3al8 - mSEMA 6A + plexin-A2

SEMA 7

3nvn, 3nvq – hSEMA 7A + plexin-C1