4dsf

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Template:STRUCTURE 4dsf

Ternary complex of Bacillus DNA Polymerase I Large Fragment F710Y, DNA duplex, and rCTP (paired with dG of template) in presence of Mn2+

Template:ABSTRACT PUBMED 22648417

About this Structure

4dsf is a 6 chain structure with sequence from Geobacillus kaustophilus hta426. Full crystallographic information is available from OCA.

Reference

  • Wang W, Wu EY, Hellinga HW, Beese LS. Structural factors that determine selectivity of a high-fidelity DNA polymerase for deoxy-, dideoxy-, and ribo-nucleotides. J Biol Chem. 2012 May 30. PMID:22648417 doi:10.1074/jbc.M112.366609
  • Wang W, Hellinga HW, Beese LS. Structural evidence for the rare tautomer hypothesis of spontaneous mutagenesis. Proc Natl Acad Sci U S A. 2011 Oct 25;108(43):17644-8. Epub 2011 Oct 17. PMID:22006298 doi:10.1073/pnas.1114496108

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