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1nys

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Revision as of 20:59, 5 December 2012 by OCA (Talk | contribs)
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Template:STRUCTURE 1nys

Crystal Structure of Activin A Bound to the ECD of ActRIIB P41

Template:ABSTRACT PUBMED 12660162

About this Structure

1nys is a 4 chain structure with sequence from Homo sapiens and Rattus norvegicus. Full crystallographic information is available from OCA.

Reference

  • Thompson TB, Woodruff TK, Jardetzky TS. Structures of an ActRIIB:activin A complex reveal a novel binding mode for TGF-beta ligand:receptor interactions. EMBO J. 2003 Apr 1;22(7):1555-66. PMID:12660162 doi:10.1093/emboj/cdg156
  • Weber D, Kotzsch A, Nickel J, Harth S, Seher A, Mueller U, Sebald W, Mueller TD. A silent H-bond can be mutationally activated for high-affinity interaction of BMP-2 and activin type IIB receptor. BMC Struct Biol. 2007 Feb 12;7:6. PMID:17295905 doi:10.1186/1472-6807-7-6

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