1py1

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Image:1py1.png

Template:STRUCTURE 1py1

Complex of GGA1-VHS domain and beta-secretase C-terminal phosphopeptide

Template:ABSTRACT PUBMED 14567678

About this Structure

1py1 is a 8 chain structure with sequence from Homo sapiens. The July 2009 RCSB PDB Molecule of the Month feature on beta-Secretase by David Goodsell is 10.2210/rcsb_pdb/mom_2009_7. Full crystallographic information is available from OCA.

Reference

  • He X, Zhu G, Koelsch G, Rodgers KK, Zhang XC, Tang J. Biochemical and structural characterization of the interaction of memapsin 2 (beta-secretase) cytosolic domain with the VHS domain of GGA proteins. Biochemistry. 2003 Oct 28;42(42):12174-80. PMID:14567678 doi:10.1021/bi035199h

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