1p4r

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Image:1p4r.png

Template:STRUCTURE 1p4r

Crystal Structure of Human ATIC in complex with folate-based inhibitor BW1540U88UD

Template:ABSTRACT PUBMED 14966129

About this Structure

1p4r is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Cheong CG, Wolan DW, Greasley SE, Horton PA, Beardsley GP, Wilson IA. Crystal structures of human bifunctional enzyme aminoimidazole-4-carboxamide ribonucleotide transformylase/IMP cyclohydrolase in complex with potent sulfonyl-containing antifolates. J Biol Chem. 2004 Apr 23;279(17):18034-45. Epub 2004 Feb 13. PMID:14966129 doi:10.1074/jbc.M313691200

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