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N-TERMINAL ACTIN-BINDING DOMAIN OF HUMAN DYSTROPHIN

Dystrophin is an essential component of skeletal muscle cells. Its N-terminal domain binds to F-actin and its C terminus binds to the dystrophin-associated glycoprotein (DAG) complex in the membrane.

Structure N-TERMINAL ACTIN-BINDING DOMAIN OF HUMAN DYSTROPHIN (PDB entry 1dxx)

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Ref1[1] Ref2 [2]

  1. Nadeau D, Marchand C. Change in the kinetics of sulphacetamide tissue distribution in Walker tumor-bearing rats. Drug Metab Dispos. 1975 Nov-Dec;3(6):565-76. PMID:1234
  2. Rubinstein MH. A new granulation method for compressed tablets [proceedings]. J Pharm Pharmacol. 1976 Dec;28 Suppl:67P. PMID:12345
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