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The complex of wild type B-RAF and BAY439006

The complex of wild type B-RAF and BAY439006 (1uwh)
The complex of wild type B-RAF and BAY439006 (1uwh)


Contents

Introduction

Structure[1]

3D View of the complex

Drag the structure with the mouse to rotate
A. Structure of B-RAF Kinase Domain B. Schematic B-RAF Primary Structure
A. Structure of B-RAF Kinase Domain
B. Schematic B-RAF Primary Structure

Blablastructurepdb

Regulation

signaling ways

Other Inhibitors

drugs and inhibitor paradox

Applications in Medicine

External Ressources

PDB file for 1UWH

References

  1. ↑ Wan PT, Garnett MJ, Roe SM, Lee S, Niculescu-Duvaz D, Good VM, Jones CM, Marshall CJ, Springer CJ, Barford D, Marais R. Mechanism of activation of the RAF-ERK signaling pathway by oncogenic mutations of B-RAF. Cell. 2004 Mar 19;116(6):855-67. PMID:15035987

Protreopedia Page Contributors and Editors

Kostika Sofroni and Gilles Dupouy

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