Image:CuII coordination complex.jpg

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Three-dimensional structure of CuBD [1]

This figure was made thanks to pyMol program. We can see there the Cu(I) coordination geometry in CuBD, (PDB id: [http://www.rcsb.org/pdb/explore.do?structureId=2fk2 2fk2 Four aminoacids are forming the square pyramidal (tyr 168, his 147, his 151, and met170) There is also to water molecules (in red) : one is axial, and the other is equatorial.

references

  1. Kong GK, Adams JJ, Harris HH, Boas JF, Curtain CC, Galatis D, Masters CL, Barnham KJ, McKinstry WJ, Cappai R, Parker MW. Structural studies of the Alzheimer's amyloid precursor protein copper-binding domain reveal how it binds copper ions. J Mol Biol. 2007 Mar 16;367(1):148-61. Epub 2006 Dec 21. PMID:17239395 doi:10.1016/j.jmb.2006.12.041

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(current)23:42, 4 January 2013Andréa Mc Cann (Talk | contribs)387×29028 KBThree-dimensional structure of CuBD <ref>PMID : 17239395 </ref> This figure was made thanks to pyMol program. We can see there the Cu(I) coordination geometry in CuBD, (PDB id: [http://www.rcsb.org/pdb/explore.do?structureId=2fk2 2fk2 Four aminoacids ar

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