1vjq

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Image:1vjq.png

Template:STRUCTURE 1vjq

Designed protein based on backbone conformation of procarboxypeptidase-A (1AYE) with sidechains chosen for maximal predicted stability.

Template:ABSTRACT PUBMED 12948494

About this Structure

1vjq is a 2 chain structure. Full crystallographic information is available from OCA.

Reference

  • Dantas G, Kuhlman B, Callender D, Wong M, Baker D. A large scale test of computational protein design: folding and stability of nine completely redesigned globular proteins. J Mol Biol. 2003 Sep 12;332(2):449-60. PMID:12948494
  • Dantas G, Corrent C, Reichow SL, Havranek JJ, Eletr ZM, Isern NG, Kuhlman B, Varani G, Merritt EA, Baker D. High-resolution structural and thermodynamic analysis of extreme stabilization of human procarboxypeptidase by computational protein design. J Mol Biol. 2007 Mar 2;366(4):1209-21. Epub 2006 Dec 2. PMID:17196978 doi:10.1016/j.jmb.2006.11.080

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