1t84

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Template:STRUCTURE 1t84

Solution structure of the Wiskott-Aldrich Syndrome Protein (WASP) autoinhibited core domain complexed with (S)-wiskostatin, a small molecule inhibitor

Template:ABSTRACT PUBMED 15235593

About this Structure

1t84 is a 1 chain structure with sequence from Homo sapiens. Full experimental information is available from OCA.

Reference

  • Peterson JR, Bickford LC, Morgan D, Kim AS, Ouerfelli O, Kirschner MW, Rosen MK. Chemical inhibition of N-WASP by stabilization of a native autoinhibited conformation. Nat Struct Mol Biol. 2004 Aug;11(8):747-55. Epub 2004 Jul 4. PMID:15235593 doi:10.1038/nsmb796

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