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2chm
From Proteopedia
CRYSTAL STRUCTURE OF N2 SUBSTITUTED PYRAZOLO PYRIMIDINONES-A FLIPPED BINDING MODE IN PDE5
Template:ABSTRACT PUBMED 16759100
About this Structure
2chm is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Allerton CM, Barber CG, Beaumont KC, Brown DG, Cole SM, Ellis D, Lane CA, Maw GN, Mount NM, Rawson DJ, Robinson CM, Street SD, Summerhill NW. A novel series of potent and selective PDE5 inhibitors with potential for high and dose-independent oral bioavailability. J Med Chem. 2006 Jun 15;49(12):3581-94. PMID:16759100 doi:10.1021/jm060113e
Categories: Homo sapiens | Allerton, C M.N. | Barber, C G. | Beaumont, K C. | Brown, D G. | Cole, S M. | Ellis, D. | Lane, C A.L. | Maw, G N. | Mount, N M. | Rawson, D J. | Robinson, C M. | Street, S D.A. | Summerhill, N W. | Allosteric enzyme | Camp | Cgmp | Cgmp-binding | Chimera | Hydrolase | Inhibitor | Magnesium | Metal-binding | Nucleotide-binding | Phosphodiesterase 5 | Phosphorylation
