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2dor

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Image:2dor.png

Template:STRUCTURE 2dor

DIHYDROOROTATE DEHYDROGENASE A FROM LACTOCOCCUS LACTIS COMPLEXED WITH OROTATE

Template:ABSTRACT PUBMED 9655329

About this Structure

2dor is a 2 chain structure with sequence from Lactococcus lactis. Full crystallographic information is available from OCA.

Reference

  • Rowland P, Bjornberg O, Nielsen FS, Jensen KF, Larsen S. The crystal structure of Lactococcus lactis dihydroorotate dehydrogenase A complexed with the enzyme reaction product throws light on its enzymatic function. Protein Sci. 1998 Jun;7(6):1269-79. PMID:9655329
  • Dobritzsch D, Schneider G, Schnackerz KD, Lindqvist Y. Crystal structure of dihydropyrimidine dehydrogenase, a major determinant of the pharmacokinetics of the anti-cancer drug 5-fluorouracil. EMBO J. 2001 Feb 15;20(4):650-60. PMID:11179210 doi:10.1093/emboj/20.4.650
  • Park F, Gajiwala K, Noland B, Wu L, He D, Molinari J, Loomis K, Pagarigan B, Kearins P, Christopher J, Peat T, Badger J, Hendle J, Lin J, Buchanan S. The 1.59 A resolution crystal structure of TM0096, a flavin mononucleotide binding protein from Thermotoga maritima. Proteins. 2004 May 15;55(3):772-4. PMID:15103641 doi:http://dx.doi.org/10.1002/prot.20086

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