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2itk

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Revision as of 12:02, 7 January 2013 by OCA (Talk | contribs)
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Image:2itk.png

Template:STRUCTURE 2itk

human Pin1 bound to D-PEPTIDE

Template:ABSTRACT PUBMED 17518432

About this Structure

2itk is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Zhang Y, Daum S, Wildemann D, Zhou XZ, Verdecia MA, Bowman ME, Lucke C, Hunter T, Lu KP, Fischer G, Noel JP. Structural basis for high-affinity peptide inhibition of human Pin1. ACS Chem Biol. 2007 May 22;2(5):320-8. PMID:17518432 doi:http://dx.doi.org/10.1021/cb7000044
  • Xu GG, Zhang Y, Mercedes-Camacho AY, Etzkorn FA. A reduced-amide inhibitor of Pin1 binds in a conformation resembling a twisted-amide transition state. Biochemistry. 2011 Nov 8;50(44):9545-50. Epub 2011 Oct 18. PMID:21980916 doi:10.1021/bi201055c

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OCA

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