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2npu

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Image:2npu.png

Template:STRUCTURE 2npu

The solution structure of the rapamycin-binding domain of mTOR (FRB)

Template:ABSTRACT PUBMED 17684489

About this Structure

2npu is a 1 chain structure with sequence from Homo sapiens. Full experimental information is available from OCA.

Reference

  • Veverka V, Crabbe T, Bird I, Lennie G, Muskett FW, Taylor RJ, Carr MD. Structural characterization of the interaction of mTOR with phosphatidic acid and a novel class of inhibitor: compelling evidence for a central role of the FRB domain in small molecule-mediated regulation of mTOR. Oncogene. 2008 Jan 24;27(5):585-95. Epub 2007 Aug 6. PMID:17684489

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