2oax

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Template:STRUCTURE 2oax

Crystal structure of the S810L mutant mineralocorticoid receptor associated with SC9420

Template:ABSTRACT PUBMED 17569793

About this Structure

2oax is a 6 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Huyet J, Pinon GM, Fay MR, Fagart J, Rafestin-Oblin ME. Structural basis of spirolactone recognition by the mineralocorticoid receptor. Mol Pharmacol. 2007 Sep;72(3):563-71. Epub 2007 Jun 14. PMID:17569793 doi:10.1124/mol.107.036459

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Categories: Homo sapiens | Fagart, J. | Fay, M R. | Huyet, J. | Pinon, G M. | Rafestin-Oblin, M E. | Activating mutation | Aldosterone | Antagonist | Hypertension | Nuclear receptor | Spironolactone | Steroid receptor | Transcription | Transcription factor

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