2h5d

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Image:2h5d.png

Template:STRUCTURE 2h5d

0.9A resolution crystal structure of alpha-lytic protease complexed with a transition state analogue, MeOSuc-Ala-Ala-Pro-Val boronic acid

Template:ABSTRACT PUBMED 16834383

About this Structure

2h5d is a 2 chain structure with sequence from Lysobacter enzymogenes. Full crystallographic information is available from OCA.

Reference

  • Fuhrmann CN, Daugherty MD, Agard DA. Subangstrom crystallography reveals that short ionic hydrogen bonds, and not a His-Asp low-barrier hydrogen bond, stabilize the transition state in serine protease catalysis. J Am Chem Soc. 2006 Jul 19;128(28):9086-102. PMID:16834383 doi:http://dx.doi.org/10.1021/ja057721o

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