2hzy

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Image:2hzy.png

Template:STRUCTURE 2hzy

Mouse fumarylacetoacetate hydrolase complexes with a transition-state mimic of the complete substrate

Template:ABSTRACT PUBMED 17064256

About this Structure

2hzy is a 2 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA.

Reference

  • Bateman RL, Ashworth J, Witte JF, Baker LJ, Bhanumoorthy P, Timm DE, Hurley TD, Grompe M, McClard RW. Slow-onset inhibition of fumarylacetoacetate hydrolase by phosphinate mimics of the tetrahedral intermediate: kinetics, crystal structure and pharmacokinetics. Biochem J. 2007 Mar 1;402(2):251-60. PMID:17064256 doi:10.1042/BJ20060961

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