3clx

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Image:3clx.png

Template:STRUCTURE 3clx

Crystal structure of XIAP BIR3 domain in complex with a Smac-mimetic compound, Smac005

Template:ABSTRACT PUBMED 18851976

About this Structure

3clx is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Mastrangelo E, Cossu F, Milani M, Sorrentino G, Lecis D, Delia D, Manzoni L, Drago C, Seneci P, Scolastico C, Rizzo V, Bolognesi M. Targeting the X-linked inhibitor of apoptosis protein through 4-substituted azabicyclo[5.3.0]alkane smac mimetics. Structure, activity, and recognition principles. J Mol Biol. 2008 Dec 19;384(3):673-89. Epub 2008 Oct 7. PMID:18851976 doi:10.1016/j.jmb.2008.09.064

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