3db8

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Image:3db8.png

Template:STRUCTURE 3db8

Crystal structure of an activated (Thr->Asp) Polo-like kinase 1 (Plk1) catalytic domain in complex with Compound 041

Template:ABSTRACT PUBMED 18790636

About this Structure

3db8 is a 1 chain structure with sequence from Danio rerio. Full crystallographic information is available from OCA.

Reference

  • Hanan EJ, Fucini RV, Romanowski MJ, Elling RA, Lew W, Purkey HE, VanderPorten EC, Yang W. Design and synthesis of 2-amino-isoxazolopyridines as Polo-like kinase inhibitors. Bioorg Med Chem Lett. 2008 Oct 1;18(19):5186-9. Epub 2008 Aug 29. PMID:18790636 doi:10.1016/j.bmcl.2008.08.091

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OCA

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