This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
2z8c
From Proteopedia
Contents |
Phosphorylated insulin receptor tyrosine kinase in complex with (4-{[5-carbamoyl-4-(3-methylanilino)pyrimidin-2-yl]amino}phenyl)acetic acid
Template:ABSTRACT PUBMED 18767165
About this Structure
2z8c is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Katayama N, Orita M, Yamaguchi T, Hisamichi H, Kuromitsu S, Kurihara H, Sakashita H, Matsumoto Y, Fujita S, Niimi T. Identification of a key element for hydrogen-bonding patterns between protein kinases and their inhibitors. Proteins. 2008 Sep 2;73(4):795-801. PMID:18767165 doi:10.1002/prot.22207
Categories: Homo sapiens | Receptor protein-tyrosine kinase | Katayama, N. | Kurihara, H. | Atp-binding | Carbohydrate metabolism | Cleavage on pair of basic residue | Diabetes mellitus | Disease mutation | Glycoprotein | Kinase | Membrane | Nucleotide-binding | Phosphorylation | Receptor | Transducer | Transferase | Transmembrane | Tyrosine-protein kinase
