1xl2

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Image:1xl2.gif

1xl2, resolution 1.50Å

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HIV-1 Protease in complex with pyrrolidinmethanamine

About this Structure

1XL2 is a Single protein structure of sequence from Human immunodeficiency virus 1 with , and as ligands. Active as HIV-1 retropepsin, with EC number 3.4.23.16 Full crystallographic information is available from OCA.

Reference

An old target revisited: two new privileged skeletons and an unexpected binding mode for HIV-protease inhibitors., Specker E, Bottcher J, Lilie H, Heine A, Schoop A, Muller G, Griebenow N, Klebe G, Angew Chem Int Ed Engl. 2005 May 13;44(20):3140-4. PMID:15822136

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