2w1f
From Proteopedia
STRUCTURE DETERMINATION OF AURORA KINASE IN COMPLEX WITH INHIBITOR
Template:ABSTRACT PUBMED 19143567
About this Structure
2w1f is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Howard S, Berdini V, Boulstridge JA, Carr MG, Cross DM, Curry J, Devine LA, Early TR, Fazal L, Gill AL, Heathcote M, Maman S, Matthews JE, McMenamin RL, Navarro EF, O'Brien MA, O'Reilly M, Rees DC, Reule M, Tisi D, Williams G, Vinkovic M, Wyatt PG. Fragment-based discovery of the pyrazol-4-yl urea (AT9283), a multitargeted kinase inhibitor with potent aurora kinase activity. J Med Chem. 2009 Jan 22;52(2):379-88. PMID:19143567 doi:10.1021/jm800984v
Categories: Homo sapiens | Non-specific serine/threonine protein kinase | Berdini, V. | Boulstridge, J A. | Brien, M A.O. | Carr, M G. | Cross, D M. | Curry, J. | Devine, L A. | Early, T R. | Fazal, L. | Gill, A L. | Heathcote, M. | Howard, S. | Maman, S. | Matthews, J E. | Mcmenamin, R L. | Navarro, E F. | Rees, D C. | Reilly, M O. | Reule, M. | Tisi, D. | Vinkovic, M. | Williams, G. | Wyatt, P G. | Atp-binding | Aurora | Cancer | Cell cycle | Inhibitor | Kinase | Nucleotide-binding | Phosphoprotein | Serine/threonine-protein kinase | Transferase
