We apologize for Proteopedia being slow to respond. For the past two years, a new implementation of Proteopedia has been being built. Soon, it will replace this 18-year old system. All existing content will be moved to the new system at a date that will be announced here.
2wtw
From Proteopedia
AURORA-A INHIBITOR STRUCTURE (2ND CRYSTAL FORM)
Template:ABSTRACT PUBMED 20067443
About this Structure
2wtw is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Dodson CA, Kosmopoulou M, Richards MW, Atrash B, Bavetsias V, Blagg J, Bayliss R. Crystal structure of an Aurora-A mutant that mimics Aurora-B bound to MLN8054: insights into selectivity and drug design. Biochem J. 2010 Mar 15;427(1):19-28. PMID:20067443 doi:10.1042/BJ20091530
