3cva

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Template:STRUCTURE 3cva

Human Bcl-xL containing a Trp to Ala mutation at position 137

Template:ABSTRACT PUBMED 19161970

About this Structure

3cva is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Feng Y, Zhang L, Hu T, Shen X, Ding J, Chen K, Jiang H, Liu D. A conserved hydrophobic core at Bcl-xL mediates its structural stability and binding affinity with BH3-domain peptide of pro-apoptotic protein. Arch Biochem Biophys. 2009 Apr 1;484(1):46-54. Epub 2009 Jan 10. PMID:19161970 doi:10.1016/j.abb.2009.01.003

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