2rfn
From Proteopedia
x-ray structure of c-Met with inhibitor.
Template:ABSTRACT PUBMED 18055465
About this Structure
2rfn is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Bellon SF, Kaplan-Lefko P, Yang Y, Zhang Y, Moriguchi J, Rex K, Johnson CW, Rose PE, Long AM, O'Connor AB, Gu Y, Coxon A, Kim TS, Tasker A, Burgess TL, Dussault I. c-Met inhibitors with novel binding mode show activity against several hereditary papillary renal cell carcinoma-related mutations. J Biol Chem. 2008 Feb 1;283(5):2675-83. Epub 2007 Nov 30. PMID:18055465 doi:10.1074/jbc.M705774200
Categories: Homo sapiens | Receptor protein-tyrosine kinase | Bellon, S F. | Dussault, I. | Kaplan-Lefko, P. | Moriguchi, J. | Yang, Y. | Zhang, Y. | Atp-binding | C-met hgf receptor tyrosine kinse kinase domain | Glycoprotein | Membrane | Nucleotide-binding | Phosphorylation | Proto-oncogene | Transferase | Transmembrane | Tyrosine-protein kinase
