3bar

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Template:STRUCTURE 3bar

Crystal structure of Plasmodium falciparum orotidine 5'-phosphate decarboxylase covalently modified by 6-azido-UMP

Template:ABSTRACT PUBMED 18189347

About this Structure

3bar is a 2 chain structure with sequence from Plasmodium falciparum. Full crystallographic information is available from OCA.

Reference

  • Bello AM, Poduch E, Liu Y, Wei L, Crandall I, Wang X, Dyanand C, Kain KC, Pai EF, Kotra LP. Structure-Activity Relationships of C6-Uridine Derivatives Targeting Plasmodia Orotidine Monophosphate Decarboxylase. J Med Chem. 2008 Feb 14;51(3):439-448. Epub 2008 Jan 12. PMID:18189347 doi:10.1021/jm7010673

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