3biz
From Proteopedia
Wee1 kinase complex with inhibitor PD331618
Template:ABSTRACT PUBMED 18191399
About this Structure
3biz is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Smaill JB, Lee HH, Palmer BD, Thompson AM, Squire CJ, Baker EN, Booth RJ, Kraker A, Hook K, Denny WA. Synthesis and structure-activity relationships of soluble 8-substituted 4-(2-chlorophenyl)-9-hydroxypyrrolo[3,4-c]carbazole-1,3(2H,6H)-diones as inhibitors of the Wee1 and Chk1 checkpoint kinases. Bioorg Med Chem Lett. 2008 Feb 1;18(3):929-33. Epub 2008 Jan 11. PMID:18191399 doi:10.1016/j.bmcl.2007.12.046
Categories: Homo sapiens | Non-specific protein-tyrosine kinase | Baker, E N. | Dickson, J M. | Ivanovic, I. | Squire, C J. | Atp-binding | Cell cycle | Cell division | Inhibitor complex | Kinase domain | Magnesium | Metal-binding | Mitosis | Nucleotide-binding | Nucleus | Phosphoprotein | Transferase | Tyrosine-protein kinase
