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3efk

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Template:STRUCTURE 3efk

Structure of c-Met with pyrimidone inhibitor 50

Template:ABSTRACT PUBMED 18763753

About this Structure

3efk is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • D'Angelo ND, Bellon SF, Booker SK, Cheng Y, Coxon A, Dominguez C, Fellows I, Hoffman D, Hungate R, Kaplan-Lefko P, Lee MR, Li C, Liu L, Rainbeau E, Reider PJ, Rex K, Siegmund A, Sun Y, Tasker AS, Xi N, Xu S, Yang Y, Zhang Y, Burgess TL, Dussault I, Kim TS. Design, synthesis, and biological evaluation of potent c-Met inhibitors. J Med Chem. 2008 Sep 25;51(18):5766-79. PMID:18763753 doi:10.1021/jm8006189

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