3efk
From Proteopedia
Structure of c-Met with pyrimidone inhibitor 50
Template:ABSTRACT PUBMED 18763753
About this Structure
3efk is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- D'Angelo ND, Bellon SF, Booker SK, Cheng Y, Coxon A, Dominguez C, Fellows I, Hoffman D, Hungate R, Kaplan-Lefko P, Lee MR, Li C, Liu L, Rainbeau E, Reider PJ, Rex K, Siegmund A, Sun Y, Tasker AS, Xi N, Xu S, Yang Y, Zhang Y, Burgess TL, Dussault I, Kim TS. Design, synthesis, and biological evaluation of potent c-Met inhibitors. J Med Chem. 2008 Sep 25;51(18):5766-79. PMID:18763753 doi:10.1021/jm8006189
Categories: Homo sapiens | Receptor protein-tyrosine kinase | Angelo, N D. | Bellon, S F. | Dussault, I. | Whittington, D. | Atp-binding | C-met | Disease mutation | Glycoprotein | Kinase | Kinase inhibitor pyrimidone | Membrane | Nucleotide-binding | Phosphoprotein | Proto-oncogene | Receptor | Transferase | Transmembrane | Tyrosine-protein kinase