3e7j

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Image:3e7j.png

Template:STRUCTURE 3e7j

HeparinaseII H202A/Y257A double mutant complexed with a heparan sulfate tetrasaccharide substrate

Template:ABSTRACT PUBMED 20404324

About this Structure

3e7j is a 2 chain structure with sequence from Pedobacter heparinus. Full crystallographic information is available from OCA.

Reference

  • Shaya D, Zhao W, Garron ML, Xiao Z, Cui Q, Zhang Z, Sulea T, Linhardt RJ, Cygler M. Catalytic mechanism of heparinase II investigated by site-directed mutagenesis and the crystal structure with its substrate. J Biol Chem. 2010 Jun 25;285(26):20051-61. Epub 2010 Apr 19. PMID:20404324 doi:10.1074/jbc.M110.101071

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