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2bk2

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Image:2bk2.png

Template:STRUCTURE 2bk2

The prepore structure of pneumolysin, obtained by fitting the alpha carbon trace of perfringolysin O into a cryo-EM map

Template:ABSTRACT PUBMED 15851031

About this Structure

2bk2 is a 1 chain structure with sequence from Clostridium perfringens. Full crystallographic information is available from OCA.

Reference

  • Tilley SJ, Orlova EV, Gilbert RJ, Andrew PW, Saibil HR. Structural basis of pore formation by the bacterial toxin pneumolysin. Cell. 2005 Apr 22;121(2):247-56. PMID:15851031 doi:http://dx.doi.org/10.1016/j.cell.2005.02.033
  • Rossjohn J, Feil SC, McKinstry WJ, Tweten RK, Parker MW. Structure of a cholesterol-binding, thiol-activated cytolysin and a model of its membrane form. Cell. 1997 May 30;89(5):685-92. PMID:9182756

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