This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
1okq
From Proteopedia
LAMININ ALPHA 2 CHAIN LG4-5 DOMAIN PAIR, CA1 SITE MUTANT
Template:ABSTRACT PUBMED 12963372
About this Structure
1okq is a 1 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA.
Reference
- Wizemann H, Garbe JH, Friedrich MV, Timpl R, Sasaki T, Hohenester E. Distinct requirements for heparin and alpha-dystroglycan binding revealed by structure-based mutagenesis of the laminin alpha2 LG4-LG5 domain pair. J Mol Biol. 2003 Sep 19;332(3):635-42. PMID:12963372
- Tisi D, Talts JF, Timpl R, Hohenester E. Structure of the C-terminal laminin G-like domain pair of the laminin alpha2 chain harbouring binding sites for alpha-dystroglycan and heparin. EMBO J. 2000 Apr 3;19(7):1432-40. PMID:10747011 doi:http://dx.doi.org/10.1093/emboj/19.7.1432
