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1hkn

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Image:1hkn.png

Template:STRUCTURE 1hkn

A COMPLEX BETWEEN ACIDIC FIBROBLAST GROWTH FACTOR AND 5-AMINO-2-NAPHTHALENESULFONATE

Template:ABSTRACT PUBMED 12676958

About this Structure

1hkn is a 6 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Fernandez-Tornero C, Lozano RM, Redondo-Horcajo M, Gomez AM, Lopez JC, Quesada E, Uriel C, Valverde S, Cuevas P, Romero A, Gimenez-Gallego G. Leads for development of new naphthalenesulfonate derivatives with enhanced antiangiogenic activity: crystal structure of acidic fibroblast growth factor in complex with 5-amino-2-naphthalene sulfonate. J Biol Chem. 2003 Jun 13;278(24):21774-81. Epub 2003 Apr 3. PMID:12676958 doi:10.1074/jbc.M212833200
  • Lozano RM, Jimenez M, Santoro J, Rico M, Gimenez-Gallego G. Solution structure of acidic fibroblast growth factor bound to 1,3, 6-naphthalenetrisulfonate: a minimal model for the anti-tumoral action of suramins and suradistas. J Mol Biol. 1998 Sep 4;281(5):899-915. PMID:9719643

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