1t7b

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Template:STRUCTURE 1t7b

Crystal structure of mutant Lys8Gln of scorpion alpha-like neurotoxin BmK M1 from Buthus martensii Karsch

Template:ABSTRACT PUBMED 15321715

About this Structure

1t7b is a 1 chain structure with sequence from Mesobuthus martensii. Full crystallographic information is available from OCA.

Reference

  • Guan RJ, Xiang Y, He XL, Wang CG, Wang M, Zhang Y, Sundberg EJ, Wang DC. Structural mechanism governing cis and trans isomeric states and an intramolecular switch for cis/trans isomerization of a non-proline peptide bond observed in crystal structures of scorpion toxins. J Mol Biol. 2004 Aug 27;341(5):1189-204. PMID:15321715 doi:http://dx.doi.org/10.1016/j.jmb.2004.06.067
  • He XL, Li HM, Zeng ZH, Liu XQ, Wang M, Wang DC. Crystal structures of two alpha-like scorpion toxins: non-proline cis peptide bonds and implications for new binding site selectivity on the sodium channel. J Mol Biol. 1999 Sep 10;292(1):125-35. PMID:10493862 doi:http://dx.doi.org/10.1006/jmbi.1999.3036
  • Shao F, Xiong YM, Zhu RH, Ling MH, Chi CW, Wang DC. Expression and purification of the BmK M1 neurotoxin from the scorpion Buthus martensii Karsch. Protein Expr Purif. 1999 Dec;17(3):358-65. PMID:10600453 doi:http://dx.doi.org/10.1006/prep.1999.1127
  • Xiong YM, Ling MH, Wang DC, Chi CW. The CDNA and genomic DNA sequences of a mammalian neurotoxin from the scorpion Buthus martensii Karsch. Toxicon. 1997 Jul;35(7):1025-31. PMID:9248001
  • Ye X, Bosmans F, Li C, Zhang Y, Wang DC, Tytgat J. Structural basis for the voltage-gated Na+ channel selectivity of the scorpion alpha-like toxin BmK M1. J Mol Biol. 2005 Nov 4;353(4):788-803. Epub 2005 Sep 22. PMID:16209876 doi:10.1016/j.jmb.2005.08.068

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