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2nm1

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Image:2nm1.png

Template:STRUCTURE 2nm1

Structure of BoNT/B in complex with its protein receptor

Template:ABSTRACT PUBMED 17167421

About this Structure

2nm1 is a 2 chain structure with sequence from Clostridium botulinum and Rattus norvegicus. Full crystallographic information is available from OCA.

Reference

  • Jin R, Rummel A, Binz T, Brunger AT. Botulinum neurotoxin B recognizes its protein receptor with high affinity and specificity. Nature. 2006 Dec 21;444(7122):1092-5. Epub 2006 Dec 13. PMID:17167421 doi:http://dx.doi.org/10.1038/nature05387
  • Swaminathan S, Eswaramoorthy S. Structural analysis of the catalytic and binding sites of Clostridium botulinum neurotoxin B. Nat Struct Biol. 2000 Aug;7(8):693-9. PMID:10932256
  • Jayaraman S, Eswaramoorthy S, Ahmed SA, Smith LA, Swaminathan S. N-terminal helix reorients in recombinant C-fragment of Clostridium botulinum type B. Biochem Biophys Res Commun. 2005 Apr 29;330(1):97-103. PMID:15781237 doi:http://dx.doi.org/10.1016/j.bbrc.2005.02.123

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