2l6t

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Image:2l6t.png

Template:STRUCTURE 2l6t

Efficacy of an HIV-1 entry inhibitor targeting the GP41 fusion peptide

Template:ABSTRACT PUBMED 21178138

About this Structure

2l6t is a 1 chain structure. Full experimental information is available from OCA.

Reference

  • Forssmann WG, The YH, Stoll M, Adermann K, Albrecht U, Barlos K, Busmann A, Canales-Mayordomo A, Gimenez-Gallego G, Hirsch J, Jimenez-Barbero J, Meyer-Olson D, Munch J, Perez-Castells J, Standker L, Kirchhoff F, Schmidt RE. Short-term monotherapy in HIV-infected patients with a virus entry inhibitor against the gp41 fusion peptide. Sci Transl Med. 2010 Dec 22;2(63):63re3. PMID:21178138 doi:10.1126/scitranslmed.3001697
  • Munch J, Standker L, Adermann K, Schulz A, Schindler M, Chinnadurai R, Pohlmann S, Chaipan C, Biet T, Peters T, Meyer B, Wilhelm D, Lu H, Jing W, Jiang S, Forssmann WG, Kirchhoff F. Discovery and optimization of a natural HIV-1 entry inhibitor targeting the gp41 fusion peptide. Cell. 2007 Apr 20;129(2):263-75. PMID:17448989 doi:S0092-8674(07)00328-5

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