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2zr1

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Image:2zr1.png

Template:STRUCTURE 2zr1

Agglutinin from Abrus Precatorius

Template:ABSTRACT PUBMED 20433687

About this Structure

2zr1 is a 4 chain structure with sequence from Abrus precatorius. Full crystallographic information is available from OCA.

Reference

  • Cheng J, Lu TH, Liu CL, Lin JY. A biophysical elucidation for less toxicity of agglutinin than abrin-a from the seeds of Abrus precatorius in consequence of crystal structure. J Biomed Sci. 2010 Apr 30;17:34. PMID:20433687 doi:10.1186/1423-0127-17-34
  • Bagaria A, Surendranath K, Ramagopal UA, Ramakumar S, Karande AA. Structure-function analysis and insights into the reduced toxicity of Abrus precatorius agglutinin I in relation to abrin. J Biol Chem. 2006 Nov 10;281(45):34465-74. Epub 2006 Jun 13. PMID:16772301 doi:http://dx.doi.org/10.1074/jbc.M601777200
  • Liu CL, Tsai CC, Lin SC, Wang LI, Hsu CI, Hwang MJ, Lin JY. Primary structure and function analysis of the Abrus precatorius agglutinin A chain by site-directed mutagenesis. Pro(199) Of amphiphilic alpha-helix H impairs protein synthesis inhibitory activity. J Biol Chem. 2000 Jan 21;275(3):1897-901. PMID:10636890
  • Tahirov TH, Lu TH, Liaw YC, Chen YL, Lin JY. Crystal structure of abrin-a at 2.14 A. J Mol Biol. 1995 Jul 14;250(3):354-67. PMID:7608980 doi:http://dx.doi.org/10.1006/jmbi.1995.0382

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