3f4j

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Image:3f4j.png

Template:STRUCTURE 3f4j

Crystal structure of LeuT bound to glycine and sodium

Template:ABSTRACT PUBMED 19074341

About this Structure

3f4j is a 1 chain structure with sequence from Aquifex aeolicus. Full crystallographic information is available from OCA.

Reference

  • Singh SK, Piscitelli CL, Yamashita A, Gouaux E. A competitive inhibitor traps LeuT in an open-to-out conformation. Science. 2008 Dec 12;322(5908):1655-61. PMID:19074341 doi:322/5908/1655
  • Singh SK, Yamashita A, Gouaux E. Antidepressant binding site in a bacterial homologue of neurotransmitter transporters. Nature. 2007 Aug 23;448(7156):952-6. Epub 2007 Aug 8. PMID:17687333 doi:10.1038/nature06038
  • Yamashita A, Singh SK, Kawate T, Jin Y, Gouaux E. Crystal structure of a bacterial homologue of Na+/Cl--dependent neurotransmitter transporters. Nature. 2005 Sep 8;437(7056):215-23. Epub 2005 Jul 24. PMID:16041361 doi:10.1038/nature03978

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