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3fxv

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Image:3fxv.png

Template:STRUCTURE 3fxv

Identification of an N-oxide pyridine GW4064 analogue as a potent FXR agonist

Template:ABSTRACT PUBMED 19328688

About this Structure

3fxv is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Feng S, Yang M, Zhang Z, Wang Z, Hong D, Richter H, Benson GM, Bleicher K, Grether U, Martin RE, Plancher JM, Kuhn B, Rudolph MG, Chen L. Identification of an N-oxide pyridine GW4064 analog as a potent FXR agonist. Bioorg Med Chem Lett. 2009 May 1;19(9):2595-8. Epub 2009 Mar 9. PMID:19328688 doi:10.1016/j.bmcl.2009.03.008

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