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3hl5

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Image:3hl5.png

Template:STRUCTURE 3hl5

Crystal structure of XIAP BIR3 with CS3

Template:ABSTRACT PUBMED 19492850

About this Structure

3hl5 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Ndubaku C, Varfolomeev E, Wang L, Zobel K, Lau K, Elliott LO, Maurer B, Fedorova AV, Dynek JN, Koehler M, Hymowitz SG, Tsui V, Deshayes K, Fairbrother WJ, Flygare JA, Vucic D. Antagonism of c-IAP and XIAP proteins is required for efficient induction of cell death by small-molecule IAP antagonists. ACS Chem Biol. 2009 Jul 17;4(7):557-66. PMID:19492850 doi:10.1021/cb900083m

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