2y3a

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Template:STRUCTURE 2y3a

Contents 1 CRYSTAL STRUCTURE OF P110BETA IN COMPLEX WITH ICSH2 OF P85BETA AND THE DRUG GDC-0941 2 About this Structure 3 See Also 4 Reference

CRYSTAL STRUCTURE OF P110BETA IN COMPLEX WITH ICSH2 OF P85BETA AND THE DRUG GDC-0941

Template:ABSTRACT PUBMED 21362552

About this Structure

2y3a is a 2 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA.

See Also

• Phosphoinositide 3-Kinases
• Phsphatidylinositol 3-kinase

Reference

• Zhang X, Vadas O, Perisic O, Anderson KE, Clark J, Hawkins PT, Stephens LR, Williams RL. Structure of Lipid Kinase p110beta/p85beta Elucidates an Unusual SH2-Domain-Mediated Inhibitory Mechanism. Mol Cell. 2011 Mar 4;41(5):567-78. PMID:21362552 doi:10.1016/j.molcel.2011.01.026