2wpc

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Template:STRUCTURE 2wpc

Contents 1 TRYPANOSOMA BRUCEI TRYPANOTHIONE REDUCTASE IN COMPLEX WITH 3,4-DIHYDROQUINAZOLINE INHIBITOR (DDD00073357) 2 About this Structure 3 See Also 4 Reference

TRYPANOSOMA BRUCEI TRYPANOTHIONE REDUCTASE IN COMPLEX WITH 3,4-DIHYDROQUINAZOLINE INHIBITOR (DDD00073357)

Template:ABSTRACT PUBMED 21851087

About this Structure

2wpc is a 4 chain structure with sequence from Trypanosoma brucei. Full crystallographic information is available from OCA.

See Also

• Trypanothione reductase

Reference

• Patterson S, Alphey MS, Jones DC, Shanks EJ, Street IP, Frearson JA, Wyatt PG, Gilbert IH, Fairlamb AH. Dihydroquinazolines as a Novel Class of Trypanosoma brucei Trypanothione Reductase Inhibitors: Discovery, Synthesis, and Characterization of their Binding Mode by Protein Crystallography. J Med Chem. 2011 Oct 13;54(19):6514-30. Epub 2011 Sep 1. PMID:21851087 doi:10.1021/jm200312v