Ribosomal protein S21

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Template:STRUCTURE 3kc4

Ribosomal protein S21 (RPS21) is one of the 22 proteins which belong to the of the bacterial ribosome. It is found only in eubacteria, plant chloroplasts and mammalian mitochondria. It is involved in the initiation of polypeptide synthesis. The images at the left and at the right correspond to one representative RPS21, i.e. the crystal structure of Ribosomal protein S21 from Escherichia coli (3kc4, chain U).

3D Structures of Ribosomal protein S21

Updated on 11-March-2013

S21 in small ribosomal subunit

3kc4 – EcRPS21 in 30S ribosomal subunit – Escherichia coli
3i1m, 3i1o, 3df1, 3df3, 2vho, 2vhp, 2avy, 2aw7, 3ofa, 3ofb, 3ofx, 3ofy, 3ofo, 3ofp, 3or9, 3ora - EcRPS21 in 30S ribosomal subunit+16S RRNA
3bbn - RPS21 in 30S ribosomal subunit+16S RRNA – Cryo-EM – spinach

S21 in small ribosomal subunit+ chain release factor

3uoq – EcRPS21 + 16S RRNA + mRNA + chain release factor 3

S21 in small ribosomal subunit+tRNA+mRNA

2i2p, 2i2u - EcRPS21 in 30S ribosomal subunit+16S RRNA+tRNA Phe+mRNA
3j0u, 3j0v, 3j0x, 3j0z, 3j10 – EcRPS21 in 30S ribosomal subunit+ A-site tRNA + P-site tRNA +16S RRNA+mRNA – Cryo-EM
3j13 – EcRPS21 in 30S ribosomal subunit+ P-site tRNA +16S RRNA+mRNA – Cryo-EM

S21 in small ribosomal subunit+P-site tRNA

2wwl - EcRPS21 in 30S ribosomal subunit+Poly-Ala chain+P-site tRNA+mRNA +16S RRNA - Escherichia coli
3i1q - EcRPS21 in 30S ribosomal subunit+P-site tRNA hairpin+mRNA
3i1s, 3i1z, 3i21 - EcRPS21 in 30S ribosomal subunit+P-site tRNA hairpin+mRNA +16S RNA

S21 in small ribosomal subunit+A-site tRNA+P-site tRNA+E-site tRNA

3e1a, 3e1c - EcRPS21 in 30S ribosomal subunit+P-site tRNA+A-site tRNA+E-site tRNA+mRNA +16S RRNA

S21 in small ribosomal subunit + antibiotics

2qbb, 2qb9, 1vs5, 1vs7, 2qan, 2qal, 2qou, 2qow, 2qoy, 2qp0, 2z4k, 2z4m, 3oaq, 3oar - EcRPS21 in 30S ribosomal subunit+16S RRNA+ antibiotic
3sfs – EcRPS21 in 30S ribosomal subunit+16S RRNA+ mRNA + RF-3 + antibiotic
4gaq, 4gas – EcRPS21 in 30S ribosomal subunit+16S RRNA+ mRNA + antibiotic

S21 in small ribosomal subunit + ribosome recycling factor

2qbd, 2qbf – EcRPS21 in 30S ribosomal subunit+16S RRNA+ribosome recycling factor
3r8n, 3r8o, 4gd1, 4gd2 – EcRPS21 in 30S ribosomal subunit+16S RRNA+ribosome recycling factor + mRNA + tRNA
2qbh, 2qbj - EcRPS21 in 30S ribosomal subunit+16S RRNA+ribosome recycling factor+gentamicin

S21 in small ribosomal subunit + elongation factor

3fih - EcRPS21 in 30S ribosomal subunit+A-site tRNA Phe+P-site tRNA+mRNA +16S RRNA+elongation factor TU
3izv – EcRPS21 in 30S ribosomal subunit+A/T-site tRNA Phe +16S RRNA+elongation factor TU
3j18 – EcRPS21 in 30S ribosomal subunit+A/T-site tRNA Phe +16S RRNA+ mRNA + SSRA-binding protein + formyl-Met specific initiator tRNA + elongation factor G – Cryo-EM
3izw – EcRPS21 in 30S ribosomal subunit+A-site tRNA Phe +mRNA +16S RRNA+elongation factor TU
1s1h - yRPS21 in 40S ribosomal subunit+18S RRNA+elongation factor 2 – Cryo-EM – yeast

S21 in small ribosomal subunit + various proteins

3j00 – EcRPS21 in 30S ribosomal subunit + 16S RRNA + mRNA + FTSQ + apolipoprotein A-I - Cryo EM
2ykr – EcRPS21 + 16S RRNA + GMPPNP + GTPase RSGA
4a2i – EcRPS21 + 16S RRNA + GTPase RSGA – Cryo EM
4adv - EcRPS21 + 16S RRNA + methyltransferase – Cryo EM
4a2i – EcRPS21 + 16S RRNA + GTPase RSGA – Cryo EM

S21 in small 40S ribosomal subunit + various proteins

3iz6 – RPS2121 in 40S ribosomal subunit+ RACK1 – yeast - Cryo-EM
3u5c, 3u5g - yRPS21 in 40S ribosomal subunit+ RACK1 + suppressor protein SMT1

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Michal Harel, Joel L. Sussman, Alexander Berchansky, Jaime Prilusky

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