3i5n
From Proteopedia
Crystal structure of c-Met with triazolopyridazine inhibitor 13
Template:ABSTRACT PUBMED 19819693
About this Structure
3i5n is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Boezio AA, Berry L, Albrecht BK, Bauer D, Bellon SF, Bode C, Chen A, Choquette D, Dussault I, Fang M, Hirai S, Kaplan-Lefko P, Larrow JF, Lin MH, Lohman J, Potashman MH, Qu Y, Rex K, Santostefano M, Shah K, Shimanovich R, Springer SK, Teffera Y, Yang Y, Zhang Y, Harmange JC. Discovery and optimization of potent and selective triazolopyridazine series of c-Met inhibitors. Bioorg Med Chem Lett. 2009 Nov 15;19(22):6307-12. Epub 2009 Sep 27. PMID:19819693 doi:10.1016/j.bmcl.2009.09.096
Categories: Homo sapiens | Receptor protein-tyrosine kinase | Bellon, S F. | Boezio, A A. | Long, A M. | Whittington, D A. | Atp-binding | Disease mutation | Disulfide bond | Glycoprotein | Hgf/sf | Kinase | Membrane | Nucleotide-binding | Phosphoprotein | Proto-oncogene | Receptor | Receptor tyrosine kinase | Rtk | Scatter factor receptor | Transferase | Transmembrane | Tyrosine-protein kinase
