3hhk

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Template:STRUCTURE 3hhk

HCV NS5b polymerase complex with a substituted benzothiadizine

Template:ABSTRACT PUBMED 19515564

About this Structure

3hhk is a 2 chain structure with sequence from Hepatitis c virus subtype 1b. Full crystallographic information is available from OCA.

Reference

  • Shaw AN, Tedesco R, Bambal R, Chai D, Concha NO, Darcy MG, Dhanak D, Duffy KJ, Fitch DM, Gates A, Johnston VK, Keenan RM, Lin-Goerke J, Liu N, Sarisky RT, Wiggall KJ, Zimmerman MN. Substituted benzothiadizine inhibitors of Hepatitis C virus polymerase. Bioorg Med Chem Lett. 2009 Aug 1;19(15):4350-3. Epub 2009 May 28. PMID:19515564 doi:10.1016/j.bmcl.2009.05.091

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