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3hxb

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Template:STRUCTURE 3hxb

Engineered RabGGTase in complex with a peptidomimetic inhibitor (compound 6)

Template:ABSTRACT PUBMED 19894725

About this Structure

3hxb is a 2 chain structure with sequence from Rattus norvegicus. Full crystallographic information is available from OCA.

Reference

  • Tan KT, Guiu-Rozas E, Bon RS, Guo Z, Delon C, Wetzel S, Arndt S, Alexandrov K, Waldmann H, Goody RS, Wu YW, Blankenfeldt W. Design, synthesis, and characterization of peptide-based rab geranylgeranyl transferase inhibitors. J Med Chem. 2009 Dec 24;52(24):8025-37. PMID:19894725 doi:10.1021/jm901117d

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